Industrial sector has been competing against agricultural, and residential sectors for water resources to sustain and develop society and economy (Mol and van Buuren, 2003). Rapid industrialization (Geng et al., 2012) and unawareness of the fresh water stress result in continued increase in industrial water use (Florke et al., 2013; Xiao-jun et al., 2012). Enhancement of sustainable industrial development is required to prevent water becoming a limiting factor for economic development. As a part of ENTIRE project, the study aims to design and model a technical framework for water and wastewater services for optimizing industrial fresh water utilization of industrial areas and their associated residential areas. The objective will be met in 3 steps: (1) first focuses on analysing and mapping the natural water resources and water uses of the industries in quantity, quality, and time; (2) based on various treatment and storage processes dealing with the relevant water parameters for quality, flows and storage, a conceptual model that applies three strategies defined in Urban Harvest Approach: demand minimization, output minimization, and multi-sourcing will be proposed; (3) conceptual model will be converted into a dynamic model that is developed for designing multi-sourcing and circular based water systems that match the quantitative, qualitative and temporal needs of the industries, considering the economy of scales for the various processes for treatment and storage. Result is a spatial relevant solution for the specific industrial zone, but through the model a scalable and repetitive character for other sites in Vietnamese regions is available.