Urban flood water originated from rainfall runoff, sewage or river contains high microorganism concentration. As a consequence, if people expose to flood water and ingest contaminated water, it can cause waterborne disease, for example: diarrhea. Moreover, urban flood may increase due to the effect of climate change and urbanization in future. The contaminated sources (such as: domestic wastewater) which impact the water quality also may change because of population growth in future. These changes, thus, may lead to increase health risk in future scenarios. The main aim of this study focuses on assessing flood-related water quality and the health risk associated with floodwater exposure in urban area in current and future flood scenarios. The study will also consider some proposed measures for improving water quality and reducing health risk related to waterborne diseases.